深圳湾实验室位于粤港澳大湾区核心引擎，是深圳新建立的生命健康科学研究机构，由詹启敏院士担任实验室主任，林建华教授担任特别顾问，吴云东院士任实验室常务副主任。实验室由北京大学深圳研究生院与相关单位共同举办，协同粤港澳大湾区健康科学领域具有研究基础和应用优势的单位合作共建。深圳湾实验室将坚持“立足深圳、问题导向、汇聚人才、支撑发展”的发展理念，建设世界一流生命科学和生物医药领域的学术研究中心。

分子生理学研究所重点研究领域包括（1）分子生物学基本原理如基因表达调控的动态过程及功能、DNA损伤修复机制等，（2）分子生物学技术如基因编辑、分子动态标记、基因治疗等，（3）基本的生理学问题如传染病感染机制、神经免疫调节、睡眠机理等。核心研究方向为重要生物学过程的分子生物学机理和先进分子生物学技术的开发及应用。

分子生理学研究所将借鉴全球顶级生物学研究机构的成功经验，结合国内科研改革方向，通过在研究所建立合理的科研运作机制、打造顶尖的科研平台和研究资源、引进一流的科学家团队、与国内外顶级科研单位建立长期稳定的合作，将研究所建设为国际一流的研发机构。

分子生理学研究所可共享以下研究平台：

分子成像平台

将搭载超分辨成像系统、活细胞工作平台、常用共聚焦显微镜，提供最为先进的成像技术并进行新型成像技术的开发。

分子文库中心

将构建全基因组筛选用的基因文库，建立常用病毒包装系统，为进一步的高通量筛选、分子进化、基因治疗等研究提供支撑。

动物中心

第一期将建设500m2左右的SPF级别鼠房，容纳小鼠笼位2000个左右，保证相关动物实验的顺利开展。随着相关研究课题的开展，将建设8000m2的动物饲养空间，大小鼠笼位各12000笼。

高通量筛选平台

将搭载全自动高通量筛选设备，可在细胞、线虫、斑马鱼等系统中进行小规模化合物筛选、高通量遗传筛选（siRNAs、 shRNAs、 cDNAs、CRISPR）以及高通量筛选数据的处理等，为科学家提供全方位的筛选实验设计、技术指导和数据分析。

基因组学中心

将搭建高通量测序系统和生物信息学分析平台，是研究基因转录调控等重要问题的基础。

蛋白质组学平台

将搭建多种蛋白质质谱分析系统，为科学家提供先进的基于高分辨质谱技术的蛋白质组学技术支撑。

转基因动物中心

将提供基本的转基因动物构建、动物净化、胚胎冻存等服务。

一、招聘对象：

海内外知名院校及科研机构中，从事生命科学前沿研究的各层次人才。岗位包括首席科学家，资深研究员（tenured），特聘研究员（预聘，tenure-track）。

二、应聘条件：

【资深研究职位】：主要包括 首席科学家，资深研究员（tenured）

具有博士学位，应在海内外知名高校、科研院所担任副教授、副研究员以上或相当职务。

【预聘研究职位】：主要包括 特聘研究员（预聘，tenure-track）

具有博士学位；应聘人学术水平和资历应达到担任海内外知名高校助理教授或副教授职务的相应标准；首聘期5-6年，后通过评估决定是否获得长聘岗位（tenured）。

三、薪酬福利与其他待遇：

1. 薪酬和福利待遇

提供具有国际竞争力的薪酬待遇；协助申请深圳市人才安居房或高层次人才补贴。

2. 科研保障

独立实验和办公空间；参照国际一流研究院所提供启动经费，根据申请人研究计划面议；协助申请各类人才经费；可配研究助手，研究生名额优先。

四、应聘材料及联系方式：

应聘材料：

1 个人中英文简历

2 自荐信

3发表学术成果列表

4 研究总结与研究计划（含研究经费预算）

5 三名推荐人姓名及联系方式

将上述材料发送至深圳湾实验室人事部招聘邮箱：HR_PI@szbl.ac.cn，邮件标题注明：应聘岗位+本人姓名+所学专业+高校师资网。

如需了解更多深圳湾实验室信息，请浏览官方网站： www.szbl.ac.cn

深圳湾实验室分子生理学研究所为全球学术人才提供公平的申请机会，招聘常年进行中，诚邀海内外各层次杰出学术人才加盟！

Recruitment of Faculty for Institute of Molecular Physiology

of Shenzhen Bay Laboratory

About the Shenzhen Bay Laboratory（SZBL）

The Shenzhen Bay Laboratory (SZBL) is a newly established institution focus on health sciences research, located in the heart of the China Great Bay Area. It was launched by the Peking University and Shenzhen city with an initial budget of $2 billion USD/5yr. SZBL aspires to be a world-class research institution and intellectual destination dedicated to understanding the fundamental biology underlying health and diseases while spurring solutions to the grand challenges confronting our world’s population and human well-being. The mission of the SZBL is to create a new research model to boost the health sciences and nurture the innovation-oriented biotechnology industry.

About the Institute of Molecular Physiology of SZBL

The Institute of Molecular Physiology focuses research in two major areas - the molecular mechanism in important biological process and the development and application of advanced techniques in molecular biology. The former will primarily focus on the replication, repair, expression and regulation of genes and other basic molecular biological events as such and associated mechanisms during the significant processes of genetic proliferation, aging and lesion. The latter carries out research and application of molecular biotechniques such as molecular evolution, gene editing, molecular marker for detection and gene therapy. Research will be both basic and applied, covering up four major aspects including gene repair and duplication, regulation of gene expression, molecular mechanisms of infectious diseases, techniques of molecular biology. Though these research and discovery, the Institute will effectively unite research from both basic and applied to facilitate the translation of research results.

The Institute of Molecular Physiology can share the following research platforms:

- Molecular Imaging Platform

It will be equipped with a super-resolution imaging system, a living cell working platform, and confocal microscopes to provide the most advanced imaging technology and develop new imaging technologies.

- Gene Library

A gene library for genome-wide screening will be constructed, and virus packaging systems will be established to provide support for further research on high-throughput screening, molecular evolution, and gene therapy.

- Animal Center

An SPF-level animal house of about 500m2 will first be constructed to accommodate about 2,000 mouse cages to facilitate relevant animal experiments. Further construction of about 8000m2 will provide animal breeding spaces for 12,000 cages of mouse and rat, respectively.

- High-throughput Screening Platform

It will be equipped with a full-automatic high-throughput screening device, which can perform small-scale compound screening, high-throughput genetic screening (siRNAs,shRNAs,cDNAs,CRISPR) and processing of high-throughput screening data in cells, nematodes, zebrafish and other systems, providing comprehensive screening experiment design, technical guidance and data analysis in scientific research.

- Genomics Center

A high-throughput sequencing system and a bioinformatics analysis platform will be built, which will be vital and fundamental for scientific research such as gene transcription regulation.

- Proteomics Platform

A variety of protein mass spectrometry systems will be established to provide advanced proteomics technology based on high-resolution mass spectrometry for scientific research.

- Transgenic Animal Center

It will provide a variety of scientific service, including transgenic animal construction, animal purification, embryo cryopreservation and so on.

Whom we’re looking for

Institute of Molecular Physiology of SZBL strives to deliver cutting-edge technology to the global scientific community through worldwide innovation and collaboration with experts and we are looking for the brightest minds to help us achieve our goals.

We are looking to fill multiple faculty positions at all ranks. Applicants should have a doctoral degree in biology, chemistry, pharmacy and medicine or closely related fields. Postdoctoral experience is required for a junior position (Assistant Professor). Applicants for senior positions are expected to have a demonstrated publication and funding record indicative of a leading scientist.

The applicant can identify which of the above areas is his or her primary areas. Review of applications will start April 2019, but positions will remain open until filled.

What is offered

Startup package and salaries will be competitive at an international level. A package of fringe benefits that include health and retirement benefits. The SZBL will also help applicants apply for national and local talent programs.

Your Application

The Institute of Molecular Physiology of SZBL is an equal opportunity employer and welcomes applicants from all sections of the community.

Required Application documents:

1.    Curriculum vitae

2.    Cover letter

3.    Lists of publications and research funding

4.    Research summary and proposal

5.    Name and contact details of 3 references

Contact:

Please send the application documents by email attachment to HR_PI@szbl.ac.cn

Email subject: the title of the position for which you are applying.

For more details on SZBL and our research, please visit our website: www.szbl.ac.cn

Email content: please include your contact information, name, telephone number, and any dates on which you would be unavailable for an interview. Upon request, applications will be considered confidentially.

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